In this count-down we look into the world’s most lethal handguns. There are a growing number of gun manufacturers in the world; And while one brand may be better than another, I hope you will understand why I didn’t focus on the specific brands or models. Instead, I’ve assembled this list of the world’s most powerful pistols based on their caliber, stopping power and shooting velocity. Throughout the article you will see me mention “gr” or “grain,” this refers to the weight of the bullet. The general rule is: A lighter grain bullet travels faster than a heavier grain bullet, while the heaver grain bullet penetrates deeper. So without further ado, lets get started.